Original Research Article

Prevalence of Syphilis and Associated Risk Factors in HIV Patients at a Tertiary Hospital in South - South zone, Nigeria: A Cross-Sectional Study

ISSN 2979-8582  ·  Article No. 039

Dr Onuoha-Ojeamiren Gloria Olomiekido Dr Onuoha Augunus Chidubem Iduda Ojeamiren Ajay Kumar Pajapati Azeke Olohita Diane Professor Samuel Sunday Olowo

Publication Details

Publication Date
10/08/2026
Volume / Issue
Vol 1, Issue 3 (2026)
Article No.
039
Journal
British Journal of Contemporary Research
Received
27 Jul 2026
Views
27
Downloads
14
Affiliations

Dr Onuoha-Ojeamiren Gloria Olomiekido: Medical Microbiology, College of Basics Clinical Sciences, Ambrose Alli University, Ekpoma , Nigeria

Dr Onuoha Augunus Chidubem: Chemical Pathology, College of Basics Clinical Sciences, Ambrose Alli University, Ekpoma, Nigeria

Iduda Ojeamiren: Department of Laboratory Sciences, Dartford and Gravesham NHS Trust, Kent, United Kingdom

Ajay Kumar Pajapati: Department of Laboratory Medicine, Central Hospital, South Western Railway, Hubli, Karnataka, India

Azeke Olohita Diane: Department of Family Medicine, College of Clinical Sciences, Ambrose Alli University, Ekpoma, Nigeria

Professor Samuel Sunday Olowo: Medical Microbiology, College of Basics Clinical Sciences, Ambrose Alli University, Ekpoma , Nigeria

Abstract

Background: Syphilis and human immunodeficiency virus (HIV) are both sexually transmitted and can both be contracted in a single unprotected intercourse, having a co-infection can have potential adverse effects on clinical outcomes and HIV care. Methods: This hospital-based cross-sectional study was conducted among HIV patients attending the HIV clinic at a tertiary hospital in the south-south senatorial district. Sociodemographic, behavioral, and clinical data were collected using a structured interviewer questionnaire and medical records review. Blood samples were screened for syphilis using rapid plasma reagin and confirmed with Treponema pallidum hemagglutination assay. Data were analyzed using descriptive statistics, bivariate tests, and multivariable logistic regression. Results: A total of 400 HIV positive patients were enrolled; 274 (68.5%) were female,126(31.5%) were males, the mean age was 43.6 ± 1 0.1 years. Syphilis was detected in 10 participants; one male had a penile ulcer, giving an overall prevalence of 2.5% (95% CI: 1.36%-4.54%). Prevalence was significantly higher among males than females and was associated with educational level and number of sexual partners in bivariate analysis. On multivariable analysis, male sex remained the only independent predictor of syphilis Conclusion: Syphilis prevalence was low in the patients. Male sex was the only independent risk factor identified, there is a need for routine syphilis screening within HIV care, particularly among men.

Keywords

HIV Syphilis Prevalence Risk Factors Nigeria

License

CC BY 4.0

This article is published under the Creative Commons Attribution 4.0 International License . Free to read, share, and adapt with attribution.

Cite This Article

Dr Onuoha-Ojeamiren Gloria Olomiekido, Dr Onuoha Augunus Chidubem, Iduda Ojeamiren, Ajay Kumar Pajapati, Azeke Olohita Diane, Professor Samuel Sunday Olowo (2026). Prevalence of Syphilis and Associated Risk Factors in HIV Patients at a Tertiary Hospital in South - South zone, Nigeria: A Cross-Sectional Study. British Journal of Contemporary Research, 1(3), Article 039. https://doi.org/10.67693/BJCR-JZL5YJC9
Dr Onuoha-Ojeamiren Gloria Olomiekido. “Prevalence of Syphilis and Associated Risk Factors in HIV Patients at a Tertiary Hospital in South - South zone, Nigeria: A Cross-Sectional Study.” British Journal of Contemporary Research, vol. 1, no. 3, 2026.
Dr Onuoha-Ojeamiren Gloria Olomiekido. “Prevalence of Syphilis and Associated Risk Factors in HIV Patients at a Tertiary Hospital in South - South zone, Nigeria: A Cross-Sectional Study.” British Journal of Contemporary Research 1, no. 3.

Metadata

ISSN 2979-8582
DOI Prefix 10.67693
Tracking ID BEX_JUL_26_213

British Journal of Contemporary Research

Open Access · Peer Reviewed · Published by Bexford Publishing Ltd

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