The study aims to analyse the ideological and spatial implementation of the integrated Indo-Islamic architectural methods and materials that evolved through periods of cultural interaction with Sanskritic traditions in India and South Asia. This has led to the development of distinct and hybrid structures that reflect the artistic and spiritual values of both societies. Vāstuśāstra and Islamic archetypes of architectural design are widely employed to design and reflect philosophical ideas of spirituality, harmony with nature, spatial aesthetics, and environmentally compatible spaces. Methodologically, the study has been conducted through informal interviews, field visits, and rigorous content analysis, focusing on the fundamental concepts of convergence, divergence and common ground for implementing Vāstuśāstra and Islamic architectural principles in the context of Indo-Islamic architecture in India. Since both Vedic Hinduism and Islamic ideologies emerged from distinct religious, cultural, and geographical backgrounds, they intermingled in the pan-Indian context. Their architectural traditions apparently share standard design and utilitarian objectives; nonetheless, in the Mughal architecture of India. It foregrounds the historical events of racial amalgamation that shaped the Indo-Islamic culture, art, and architectural heritage, as reflected in South Asian architectural aesthetics and proficiency.