The escalating unemployment crisis among graduates in developing economies has necessitated a paradigm shift from job-seeking to job creation. This study investigates the awareness of information-based business opportunities and entrepreneurial intentions among Library and Information Science (LIS) graduates in Nigeria. Employing a descriptive survey research design, data were collected from 387 final-year LIS students across three universities in Kwara State, Nigeria, using a structured questionnaire. Findings reveal moderate awareness of foundational infopreneurship opportunities, low awareness of advanced entrepreneurial ventures, and significant barriers including inadequate entrepreneurial curriculum content, limited access to capital, and poor technological infrastructure. Despite these challenges, respondents demonstrated moderate entrepreneurial intentions, significantly predicted by attitude towards entrepreneurial behaviour, subjective norms, perceived behavioural control, and entrepreneurship education. The study concludes that bridging the gap between awareness and entrepreneurial action requires comprehensive curriculum reform, practical exposure to infopreneurship, and supportive institutional frameworks. Recommendations include integrating practical entrepreneurship modules into LIS curricula, establishing incubation centres, and fostering university-industry partnerships. Keywords: Information entrepreneurship, infopreneurship, entrepreneurial intentions, library and information science, LIS graduates, and information-based business opportunities