ABSTRACT This paper spotlights the alarming speed at which Safe Harbor regimes are diverging in the European Union and the People’s Republic of China from passive protections for intermediaries towards both proactive obligations for due diligence and content governance. Historically, the notice-and-takedown mechanism served as the global standard for balancing Intellectual Property (IP) enforcement with digital innovation. However, this study argues that the full implementation of the EU Digital Services Act (DSA) and the 2026 Amendments to the PRC Cybersecurity Law (CSL) has effectively terminated the era of the neutral host. Through a comparative doctrinal lens, the research highlights how the EU has shifted toward a Notice and Action framework that prioritises systemic risk management and user transparency, whereas China has integrated IP protection into a broader mandate of Social Governance and administrative supervision. A critical point of friction is the expansion of the Red Flag test under Article 1197 of the PRC Civil Code, which increasingly places an affirmative burden on platforms to detect obvious infringement via automated means. This is contrasted with the EU’s nuanced Best Efforts standard under Article 17 of the CDSM Directive, which attempts to balance automated filtering with the prohibition of general monitoring. Furthermore, the paper analyses the impact of the 2026 CSL Amendments, which introduce severe administrative penalties for failing to remove infringing content, marking a departure from purely civil remedies toward state-led enforcement. The study concludes by evaluating the extraterritorial implications of these conflicting mandates and the escalating Anti-Suit Injunction conflicts, asserting that the current legal landscape necessitates a bipolar compliance strategy for multinational Online Service Providers (OSPs). This divergence not only complicates international IP enforcement harmonised under the WIPO treaties but also signals a fundamental fragmentation of the global digital economy.