The study examines personal health risk management and prevention of sexually transmitted infections amongst business education students in Imo State. it specifically examines the relationship between personal health risk identification, assessment, mitigation, monitoring and prevention of sexually transmitted infections. The study employed a correlational research design. The population of the study is made up of the 485 and 56 (541) business education students at Alvan Ikoku Federal University Owerri and Imo State College of Education Ihitte/Uboma. Using Krejcie and Morgan table of sample size determination, a sample of 226 students were taken from the two institutions proportionately. Data for the study was collected with a structured questionnaire designed by the researchers. Data was collected through physical contact with the respondents. Data collected was analysed with Mean (x̄), Standard Deviation (SD) and Pearson Product Moment Correlation Coefficient (r). Mean and standard deviation were used to analyse the research questions and Pearson Product Moment Correlation Co-efficient was used to test the hypotheses. The analysis of the data collected revealed very strong positive correlation between personal health risk identification, assessment, mitigation, monitoring and prevention of sexually transmitted infections. Based on the finding, it was recommended that: management of tertiary institutions in Imo State should invest heavily in health risk sensitization campaigns to ensure protective reproductive health practices among the students; tertiary institution administrators in Imo State should incorporate functional health risk assessment modules and accessible self-tracking checklists into the Business Education curriculum to explicitly foster preventive health behaviours among students; institutional administrators in Imo State should collaborate with healthcare professionals to organize mandatory, credit-bearing health risk mitigation workshops that equip students with practical self-assessment and infection prevention strategies; and Business Education departments of tertiary institutions in Imo State should partner with their institutions’ health services to provide students with digital health-monitoring applications to make it easier for them to track personal health metrics and sustain preventative behaviours.